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Aging & Longevity
3 entries02
Comparative Effectiveness of Metformin Versus Sulfonylureas on Exceptional Longevity in Women With Type 2 Diabetes: Target Trial Emulation
The Journals of Gerontology: Series A
03
Use of Metformin Associated with Exceptional Longevity Among Older Women
UC San Diego Today (press release)
Dementia & Alzheimer's
3 entries04
Long-term metformin use for Alzheimer's disease prevention?
Alzheimer's & Dementia
05
Association of Metformin with the Risk of Dementia: A Population-Based Retrospective Cohort Study in Taiwan
Healthcare (MDPI)
06
Metformin-based oral combination therapy and dementia risk
Alzheimer's & Dementia
Cancer
3 entries07
Metformin: A Dual-Role Player in Cancer Treatment and Prevention — A Comprehensive Systematic Review and Meta-Analysis
Medicina
08
Metformin Beyond Diabetes: A Precision Gerotherapeutic and Immunometabolic Adjuvant for Aging and Cancer
Cancers
09
The impact of metformin use on survival outcomes in colorectal cancer: A systematic review and meta-analysis
Cancer Treatment and Research Communications
Cardiometabolic Outcomes
1 entry10
Medication time of metformin and sulfonylureas and incidence of cardiovascular diseases and mortality in type 2 diabetes: a pooled cohort analysis (TLGS, MESA, ARIC)
Scientific Reports
Exercise Interaction
2 entries11
Metformin suppresses the mitochondrial and transcriptional response to exercise, revealing a conserved BCL6B-associated angiogenic program
Journal of Applied Physiology
12
Metformin blunts vascular insulin sensitivity after exercise training
Journal of Clinical Endocrinology & Metabolism
Vitamin B12 & Neuropathy
4 entries13
Effect of Metformin Use on Vitamin B12 Deficiency Over Time (EMBER): A Real-World Evidence Database Study
Endocrine Practice
14
Associations between long-term metformin use, the risk of vitamin B12 deficiency, and neuropathy: An All of Us Research Program study
Diabetes Research and Clinical Practice
15
Metformin-induced vitamin B12 deficiency: A cross-sectional study — untangling the connection
Clinical Medicine Insights: Endocrinology and Diabetes
16
Metformin-induced vitamin B12 deficiency: An underdiagnosed cause of diabetic neuropathy
World Journal of Diabetes
SGLT2 Inhibitors & GLP-1 Agonists
7 entries17
SGLT inhibitors for improving healthspan and lifespan
Progress in Cardiovascular Diseases
18
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Evaluation of the Lifetime Benefits of Metformin and SGLT2 Inhibitors in Type 2 Diabetes Mellitus Patients with Cardiovascular Disease: A Systematic Review and Two-Stage Meta-Analysis
American Journal of Cardiovascular Drugs
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21
SGLT2 inhibitors and GLP-1 receptor agonists: impact on mortality in diabetic patients with cardiovascular disease (CARDIAB cohort)
Cardiovascular Diabetology
22
23
Mechanism & Causal Inference
1 entry24
Effects of putative metformin targets on phenotypic age and leukocyte telomere length: a Mendelian randomisation study using data from the UK Biobank
The Lancet Healthy Longevity
Reviews & Commentary
3 entries25
An Updated Prioritization of Geroscience-Guided FDA-Approved Drugs Repurposed to Target Aging
Medical Research Archives
26
Metformin in 2025: Pharmacology, Clinical Applications, Safety, and Future Horizons
Wireless-Life Sciences Alliance (commentary)
27
Emerging uncertainty on the anti-aging potential of metformin
Ageing Research Reviews
For information only. Nothing on this page is medical advice.